I Personally don't think it will work in a MDD with a 133MHz bus, if you check the specs on apple's site. 2002 (high end) Quicksilvers came with a dual 1 GHz with a 133 MHz bus, MDD's introduced in 08/2002 came with the options for a (low end) dual 867 MHz with a 133 MHz bus, and a (middle) with dual 1GHz with a 167 MHz bus and a (high end) with a dual 1.25 GHz with a 167 MHz bus. The MDD's introduced in 02/2003 came with the 3 options (low end) single 1GHz, with 133MHz bus, (middle) dual 1.25 GHz with 167 bus, and (high end) dual 1.42 GHz with 167 MHz bus, these models came with a firewire 800 port. The phase out of G4's came in June 2003 with only 2 configurations, dual 1.25, and dual 1.42 both with a 167MHz bus dual boot OS 9 and OS X, no firewire 800, or bluetooth options. Questions remains what is the part number on these CPU boards that are for sale, because if they were originally intended for a 167 MHz bus it will not work on a mother board set for a 133 MHz bus, unless you hack your mother board by removing a certain resistor that will enable a 167 MHz bus.