You could relocate the /Applications folder to the second internal SSD; but it would require the use (in order to make it transparent and seamless to the OS) using terminal to create hard links in /Applications that pointed to the actual application on the second SSD. I don't think aliases will work quite correctly for this. Given the size of the OS and applications; I would not think that the first SSD would have any space issue at all and would just leave OS and apps on the first SSD. Is the machine to be used as a server or a desktop for a user. Depending on the answer I would recommend a different allocation of the drives you have as well as specific applications to be used to backup data, OS, and Applications. Please post more details about the usage and you'll get better recommendations. On May 22, 2013, at 7:57 AM, Roy v.d. Westhuizen <roy at ion.co.za> wrote: > I recently acquired a new 2.6 Ghz Mac mini with the following configuration: > 16 Gb RAM > 2 x 240 Gb Mercury Pro SSD drives internal > 1x 320 Gb 7200 external Mercury Pro HD drive > 1 x I Tb x 5400 external > 1 x 2 Tb Mercury Elite Pro external. > > I want to separate the OS and applications on the internal SSD drives. How best to do that? At the moment I am only running and saving to the first SSD drive. > The 320 Gb external must then be bootable copy of the OS and Applications folder. > The 1 Tb will contain the back-up data. > The 2Tb a Time Machine back. > > What programs are best used to accomplish this so that it operates seamlessly? ----------------------------------------------- There are only three kinds of stress; your basic nuclear stress, cooking stress, and A$$hole stress. The key to their relationship is Jello. neil