A native Mac OS X version of Pro Tools is slated to be released by year's end. For all preliminary PT 6.0 information: http://www.digidesign.com/news/hotnews/PTv6/index.cfm We (Tech Support) are not aware of how third party software will be able to communicate with our hardware under Mac OS X...in other words, we do not know if: 1- Core Audio Drivers will be released 2-Third parties will need to continue and support DAE or the Direct I/O protocol 3-ASIO drivers will still be required for software such as Cubase, Nuendo and Peak. If I were to guess, an ASIO driver will need to be developed for compatibility with Cubase SX. Since we did not write any of the previous ASIO drivers for our hardware, you should contact Steinberg regarding this issue. Best regards, Digidesign Technical Support